Intranasal lipopeptide primes lung-resident memory CD8+ T cells for long-term pulmonary protection against influenza.

@article{Deliyannis2006IntranasalLP,
  title={Intranasal lipopeptide primes lung-resident memory CD8+ T cells for long-term pulmonary protection against influenza.},
  author={Georgia Deliyannis and Katherine Kedzierska and Yuk Fai Lau and Weiguang Zeng and Stephen John Turner and David C Jackson and Lorena Elizabeth Brown},
  journal={European journal of immunology},
  year={2006},
  volume={36 3},
  pages={770-8}
}
The longevity of the influenza virus-specific CD8+ T cell response following intranasal delivery of a synthetic lipopeptide was investigated and the characteristics and location of the cells associated with viral clearance examined. The lipopeptide, incorporating an epitope for CD8+ T cells and another for CD4+ T cells with the lipid moiety S-[2,3-bis… CONTINUE READING