Intranasal insulin improves cognition and modulates-amyloid in early AD

@inproceedings{Reger2007IntranasalII,
  title={Intranasal insulin improves cognition and modulates-amyloid in early AD},
  author={Mark A. Reger and Ginger S. Watson and Pattie S. Green and Charles W Wilkinson and Laura D. Baker and Brenna A. Cholerton and Mark Fishel and Stephen R. Plymate and John C. S. Breitner and W. DeGroodt and Priyesh Mehta and Suzanne Craft},
  year={2007}
}
Background: Reduced brain insulin signaling and low CSF-to-plasma insulin ratios have been observed in patients with Alzheimer disease (AD). Furthermore, intracerebroventricular or IV insulin administration improve memory, alter evoked potentials, and modulate neurotransmitters, possibly by augmenting low brain levels. After intranasal administration, insulin-like peptides follow extracellular pathways to the brain within 15 minutes. Objective: We tested the hypothesis that daily intranasal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

Potential Neuroprotective Effects of Adiponectin in Alzheimer’s Disease

International journal of molecular sciences • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Similar Papers

Loading similar papers…