Intranasal immunization with SAG1 protein of Toxoplasma gondii in association with cholera toxin dramatically reduces development of cerebral cysts after oral infection.

@article{Debard1996IntranasalIW,
  title={Intranasal immunization with SAG1 protein of Toxoplasma gondii in association with cholera toxin dramatically reduces development of cerebral cysts after oral infection.},
  author={Nathalie Debard and Dominique Buzoni-G{\^a}tel and Daniel T. Bout},
  journal={Infection and immunity},
  year={1996},
  volume={64 6},
  pages={2158-66}
}
SAG1 protein of Toxoplasma gondii was evaluated as a protective antigen in mucosal immunization with cholera toxin as an adjuvant. CBA/J mice intranasally immunized with a combination of SAG1 and cholera toxin exhibited significantly fewer cysts in the brain after oral infection with the 76K strain of T. gondii than control mice. This acquired protection… CONTINUE READING