Intranasal fentanyl and high-concentration inhaled nitrous oxide for procedural sedation: a prospective observational pilot study of adverse events and depth of sedation.

@article{Seith2012IntranasalFA,
  title={Intranasal fentanyl and high-concentration inhaled nitrous oxide for procedural sedation: a prospective observational pilot study of adverse events and depth of sedation.},
  author={Robert W Seith and Theane Theophilos and Franz E Babl},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2012},
  volume={19 1},
  pages={31-6}
}
OBJECTIVES Nitrous oxide (N(2)O) is an attractive agent for pediatric procedural sedation and analgesia (PSA) with rapid onset and offset of sedation. However, it has limited analgesic efficacy. Intranasal fentanyl (INF) provides nonparenteral analgesia. There are currently no data on the combined use of N(2)O and INF for PSA in children. The authors set out to prospectively assess the depth of sedation and incidence of adverse events when N(2)O and INF are used in combination in pediatric… CONTINUE READING
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