Intranasal delivery of a bivalent norovirus vaccine formulated in an in situ gelling dry powder

@inproceedings{Ball2017IntranasalDO,
  title={Intranasal delivery of a bivalent norovirus vaccine formulated in an in situ gelling dry powder},
  author={Jordan P Ball and Michael J Springer and Yawei Ni and Isaac Finger-Baker and Juan Mart{\'i}nez and Jessica L Hahn and John F Suber and Ashley V. DiMarco and James D. Talton and Ronald R Cobb},
  booktitle={PloS one},
  year={2017}
}
The global health community is beginning to understand the burden of norovirus-associated disease, which has a significant impact in both developed and developing countries. Norovirus virus like particle (VLP)-based vaccines are currently under development and have been shown to elicit systemic and mucosal immune responses when delivered intranasally. In the present study, we describe the use of a dry powder formulation (GelVac™) with an in situ gelling polysaccharide (GelSite™) extracted from… CONTINUE READING
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