Intranasal Ketorolac

  title={Intranasal Ketorolac},
  author={K. P. Garnock-jones},
  journal={Clinical Drug Investigation},
  • K. P. Garnock-jones
  • Published 2012
  • Medicine
  • Clinical Drug Investigation
  • Ketorolac is a member of the pyrrolo-pyrrole group of NSAIDs, and has been available in several formulations for some time, for the treatment of pain. Intranasal ketorolac has recently become available.Intranasal ketorolac was effective in providing short-term relief from postoperative pain in four well designed, phase II or III trials.In the two phase III trials, a single intranasal dose of ketorolac 31.5 mg, with or without backup analgesia, was associated with significantly higher 6-hour… CONTINUE READING
    4 Citations

    Figures, Tables, and Topics from this paper.

    Paper Mentions

    The purpose of this study is to compare the efficacy and safety of ketorolac sublingual with fentanyl intranasal used in our hospital for pain control in children undergoing bilateral… Expand
    ConditionsOtitis Media, Pain, Postoperative


    Ketorolac. A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management.
    • 312
    • Highly Influential
    Intranasal ketorolac for acute postoperative pain
    • 34
    • Highly Influential
    Pharmacokinetics and Safety of Ketorolac Following Single Intranasal and Intramuscular Administration in Healthy Volunteers
    • 48
    • Highly Influential
    Intranasal ketorolac for pain secondary to third molar impaction surgery: a randomized, double-blind, placebo-controlled trial.
    • G. Grant, D. Mehlisch
    • Medicine
    • Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
    • 2010
    • 31
    • Highly Influential
    Ketorolac 0.45% Ophthalmic Solution
    • 10
    Single dose oral analgesics for acute postoperative pain in adults.
    • 165
    • PDF
    SPRIX (ketorolac tromethamine nasal spray) US prescribing information [online]. Available from URL: 022382s000lbl.pdf [Accessed
    • 2012