Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice

@article{Pourmemar2017IntranasalCA,
  title={Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice},
  author={Ehsan Pourmemar and A. Majdi and Morteza Haramshahi and M. Talebi and S. Sadigh-Eteghad},
  journal={Experimental Gerontology},
  year={2017},
  volume={87},
  pages={16-22}
}
  • Ehsan Pourmemar, A. Majdi, +2 authors S. Sadigh-Eteghad
  • Published 2017
  • Medicine
  • Experimental Gerontology
  • Abstract Neurotrophic factors are currently being considered as pro‐cognitive therapeutic approaches for management of cognitive deficits. This study aims to evaluate the effects of intranasal (i.n.) or intraperitoneal (i.p.) administration of Cerebrolysin (CBL) (as a mixture of neurotrophic factors) on the d‐galactose‐induced oxidative stress, apoptosis and memory as well as learning impairment in mice. For this purpose, CBL (1, 2.5, 5 ml/kg/i.p.) or (1 ml/kg/i.n.), were administrated daily in… CONTINUE READING
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