Intramyocardial adiposity after myocardial infarction: new implications of a substrate for ventricular tachycardia.

@article{Pouliopoulos2013IntramyocardialAA,
  title={Intramyocardial adiposity after myocardial infarction: new implications of a substrate for ventricular tachycardia.},
  author={Jim Pouliopoulos and William W.B. Chik and Ajita Kanthan and Gopal Sivagangabalan and Michael Anthony Barry and Peter Nabil Awadallah Fahmy and Christine Midekin and Juntang Lu and Eddy Kizana and Stuart P Thomas and Aravinda Thiagalingam and Pramesh Kovoor},
  journal={Circulation},
  year={2013},
  volume={128 21},
  pages={
          2296-308
        }
}
BACKGROUND Collagen has been attributed as the principal structural substrate of ventricular tachycardia (VT) after myocardial infarction (MI), even though adiposity of myocardium after MI is well recognized histologically. We investigated the effects of intramyocardial adiposity compared with collagen on electrophysiological properties, connexin43 expression, and VT induction after MI. METHODS AND RESULTS Simultaneous left ventricular plunge-needle, noncontact mapping was performed in sheep… CONTINUE READING
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