Intramuscular pH modulates glutamate-evoked masseter muscle pain magnitude in humans.

@article{Sato2016IntramuscularPM,
  title={Intramuscular pH modulates glutamate-evoked masseter muscle pain magnitude in humans.},
  author={Hidekazu Sato and Eduardo Castrillon and Brian Edwin Cairns and Karina Haugaard Bendixen and Kelun Wang and Taneaki Nakagawa and Koichi Wajima and Pernilla Helena Svensson},
  journal={European journal of pain},
  year={2016},
  volume={20 1},
  pages={
          106-15
        }
}
BACKGROUND This study was conducted to determine whether glutamate-evoked jaw muscle pain is modulated by the acidity and temperature of the solution injected. METHODS Thirty two participants participated and received injections of high-temperature acidic (HT-A) glutamate (pH 4.8, 48 °C), high-temperature neutral (HT-N) glutamate (pH 7.0, 48 °C) and neutral temperature neutral (NT-N) glutamate (pH 7.0, 38 °C) solutions (0.5 mL) into the masseter muscle. Pain intensity was assessed with an… CONTINUE READING
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