Intramuscular ephedrine reduces emesis during the first three hours after abdominal hysterectomy

@article{Hagemann2000IntramuscularER,
  title={Intramuscular ephedrine reduces emesis during the first three hours after abdominal hysterectomy},
  author={Emma Margaret Hagemann and A. Halvorsen and {\O}. Holgersen and Tor Oddbj{\o}rn Tveit and Johan C. R{\ae}der},
  journal={Acta Anaesthesiologica Scandinavica},
  year={2000},
  volume={44}
}
Background: We tested the hypothesis that intramuscularly administered ephedrine prevents postoperative nausea and vomiting. Ephedrine is cheap, and for this indication poorly documented. 

Use of ephedrine for the short-term treatment of postoperative nausea and vomiting: a case report.

  • Elsa WuhrmanM. Clark
  • Medicine
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
  • 2011

Consensus Guidelines for Managing Postoperative Nausea and Vomiting

Evidence-based guidelines developed by an international panel of experts for the management of postoperative nausea and vomiting are presented.

Ephedrine-Dexamethasone Combination Reduces Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy

Combination group had significantly less nausea and vomiting and significantly greater number of patients with a complete response than placebo and dexamethasone groups 40%.

Comparison of efficacy Ephedrine and phenylephrine in Postoperative Vomiting in Cesarean section

It is concluded that ephedrine is the best drug for antiemetic prophylaxis before cesarean surgery based on cost and lack of side effects.

Supplemental intravenous crystalloids for the prevention of postoperative nausea and vomiting: quantitative review.

Hypovolaemia after overnight fasting is believed to exacerbate postoperative nausea and vomiting (PONV). However, data on the efficacy of supplemental i.v. crystalloids for PONV prophylaxis are

Effect of remifentanil on postoperative nausea and vomiting: a randomized pilot study

Remifentanil use only minimally affects the incidence of postoperative nausea and vomiting under sevoflurane anesthesia, suggesting that postoperative pain is managed without opioid use.

Pharmacotherapy of postoperative nausea and vomiting

The risk factors and physiology of PonV, currently available therapies, the use of a multimodal approach and the cost-effectiveness of PONV management are discussed.

Fetal and Maternal Effects of Phenylephrine and Ephedrine during Spinal Anesthesia for Cesarean Delivery

Giving phenylephrine alone by infusion at cesarean delivery was associated with a lower incidence of fetal acidosis and maternal nausea and vomiting than giving ephe-drine alone and there was no advantage to combiningphenylephrine and ephedrine.

Effect of intraoperative intravenous crystalloid infusion on postoperative nausea and vomiting after gynaecological laparoscopy: comparison of 30 and 10 ml kg(-1).

Administration of CSL 30 ml kg (-1) to healthy women undergoing day-case gynaecological laparoscopy reduced the incidence of vomiting, nausea and anti-emetic use when compared with CSL 10 ml kg(-1).

References

SHOWING 1-10 OF 17 REFERENCES

Efficacy of Ephedrine in the Prevention of Postoperative Nausea and Vomiting

It is concluded that ephedrine is an effective antiemetic agent with minimal sedative side effects in patients undergoing outpatient laparoscopy.

Prophylactic Antiemetics for Laparoscopic Cholecystectomy: Ondansetron Versus Droperidol Plus Metoclopramide

Droperidol 0.625 mg IV in combination with metoclopramide 10 mg IV was more effective in preventing postoperative nausea than was ondansetron 4mg IV in patients undergoing laparoscopic cholecystectomy, with no difference in the time to discharge.

Postoperative Nausea and Vomiting: Its Etiology, Treatment, and Prevention

Patients at high risk for postoperative emesis should receive special considerations with respect to the prophylactic use of antiemetic drugs, as suggested in a recent editorial.

Dose-response study of droperidol and metoclopramide as antiemetics for outpatient anesthesia.

A large number of papers have been published suggesting the use of droperidol, a butyrophenone derivative, as a prophylactic antiemetic agent, but the recommended doses vary widely and side effects, especially somnolence, have been reported with larger doses.

Ondansetron Versus Metoclopramide in the Treatment of Postoperative Nausea and Vomiting

Ondansetron 4 mg is more effective than metoclopramide 10 mg and placebo in the treatment of established PONV and was inversely related to the amount of fentanyl administered during anesthesia, regardless of treatment.

Can we predict who will vomit after surgery?

  • K. Korttila
  • Medicine
    Acta anaesthesiologica Scandinavica
  • 1998
A risk score is developed to predict the probability of PV in patients undergoing otolaryngological surgery and the most important factors increasing the likelihood of PV are female sex, young age, non-smoking, history of PV or motion sickness and long duration of anaesthesia.

Postoperative Nystagmus and Nausea

The presence of nystagmus in the early part of recovery from general anesthesia is associated with a higher incidence of nausea and vomiting during the first postoperative day.

Efficacy, Dose‐Response, and Safety of Ondansetron in Prevention of Postoperative Nausea and Vomiting: A Quantitative Systematic Review of Randomized Placebo‐controlled Trials

If the risk of PONV is very high, for every 100 patients receiving an adequate dose of ondansetron 20 patients will not vomit and three will have a headache who would not have had these adverse effects without the drug.

Evaluation of sixteen anti-motion sickness drugs under controlled laboratory conditions.

Abstract : The effectiveness of a drug in reducing susceptibility to acute motion sickness is readily determined in a slow rotation room (SRR) where the stressful Coriolis accelerations are under