Intramitochondrial crystalline inclusions in nonalcoholic steatohepatitis.

  title={Intramitochondrial crystalline inclusions in nonalcoholic steatohepatitis.},
  author={Stephen Hugh Caldwell and Luiz Ant{\^o}nio Rodrigues de Freitas and Sang Hoon Park and Maria Lucia Vieira Moreno and Jan A Redick and Christine A. Davis and Barbee J Sisson and James T. Patrie and Helma Pinchemel Cotrim and C K Argo and Abdullah M. S. Al-Osaimi},
  volume={49 6},
UNLABELLED Mitochondrial dysfunction is an important element in the pathogenesis of nonalcoholic steatohepatitis (NASH). Intramitochondrial crystals (IMCs) are a well-documented morphological abnormality seen on transmission electron microscopy in this disease. It has been suggested that IMCs consist of phospholipids, but their exact composition remain uncertain many years after their discovery. Micellar phase transitions of phospholipid bilayers is a well-known but little-studied phenomenon in… CONTINUE READING
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