Intramesencephalic course of the oculomotor nerve fibers: microanatomy and possible clinical significance

  title={Intramesencephalic course of the oculomotor nerve fibers: microanatomy and possible clinical significance},
  author={Zdravko Vito{\vs}evi{\'c} and Slobodan Marinkovi{\'c} and Mila {\'C}etkovi{\'c} and Bojan V Stimec and Vera N. Todorovi{\'c} and Vladimir I. Kanjuh and Milan Milisavljevi{\'c}},
  journal={Anatomical Science International},
Comprehension of the mesencephalic syndromes that affect oculomotor nerve fascicles requires a detailed knowledge of their relationship with the adjacent structures and the blood supply of the central midbrain region. This was the reasoning behind our study, which was performed in ten serially sectioned midbrains stained with cresyl violet and luxol fast blue, in three microdissected midbrains, and in two injected and cleared specimens. Three continuous groups of the intramesencephalic… Expand
Microsurgical Anatomy of the Oculomotor Nerve
The microsurgical anatomy of the oculomotor nerve is described and pictures illustrating this nerve and its surrounding connective and neurovascular structures are presented. Expand
Ptosis could be caused by oculomotor nerve palsy in the midbrain infarction. Isolated midbrain infarction is rare. We report a patient with isolated unilateral ptosis caused by partial fascicularExpand
The Oculomotor Nerve
Abstract The oculomotor nerve is the cranial nerve responsible for innervating the superior, inferior, and medial recti. It functions to rotate the eye medially, upwards, and downwards while alsoExpand
The trajectory of the medial longitudinal fasciculus in the human brain: A diffusion imaging-based tractography study.
The aim of this study is to investigate the trajectory of medial longitudinal fasciculus (MLF) and explore its anatomical relationship with the oculomotor nerve using tractography technique and GQI-based tractography is an important tool in the reconstruction and evaluation of MLF. Expand
Midbrain infarction causing oculomotor nerve palsy and ipsilateral cerebellar ataxia.
An 81-year-old woman with midbrain infarction causing pupil-sparing oculomotor nerve palsy with ipsilateral cerebellar ataxia is reported, and it may be possible to establish this entity as a new syndrome following the accumulation of more cases. Expand
Clinical Significance of the Cerebral Perforating Arteries
A strong correlation exists between certain microanatomical features, atherosclerosis, and region of supply of the perforating arteries, on the one hand, and location of the ischemic lesions on the other hand. Expand


[Intra-axial involvement of the common oculomotor nerve in mesencephalic infarctions].
It is suggested that a nuclear syndrome of the oculomotor nerve was present, because of bilateral involvement of the rectus superior in both cases, and of the levator palpebrae in one case, and the parasympathetic pupillary fibres in the other, although the infarct was unilateral. Expand
[A case of partial fascicular oculomotor paresis caused by midbrain infarction].
A 74-year-old man with an ischemic lesion in the ventral midbrain with contralateral ptosis and marked upward gaze paresis of the right eye is reported, considered to be a typical case of partial fascicular oculomotor pareis based on impairment of the caudal part of oculmotor fascicles for the levator palpebrae, superior rectus and inferior oblique muscles. Expand
Fascicular arrangement within the oculomotor nerve MRI analysis of a midbrain infarct
A patient with a partial oculomotor palsy who had impaired adduction and supraduction on the left side is treated, and a discrete lesion in the centre of the midbrain tegmentum in the rostrocaudal plane is revealed. Expand
[A case of partial fascicular oculomotor paresis].
The symptomatic differences between this and previously reported cases suggest that the topographical organization of the oculomotor fascicles for the superior rectus, levator palpebrae superioris, inferior oblique, medial Rectus, and inferior rectus muscles and the sphincter muscles of the pupils consists of fibers that lie in a lateromedial order. Expand
Partial third nerve palsy involving the superior rectus and levator palpebrae muscles and distruption of central binocular vision fusion from brain stem infarction: a case report.
This dual involvement of the superior rectus and levator palpebrae muscles supports the anatomical arrangement of the ocular motor nucleus fascicles in the midbrain, clarified by experimental studies on animals and clinical data in humans. Expand
Distribution of parasympathetic motoneurones in the oculomotor complex innervating the ciliary ganglion in the marmoset (Callithrix jacchus).
Parasympathetic motoneurones in the oculomotor complex which innervate the ciliary ganglion were identified using the horseradish peroxidase retrograde axonal tracer technique and there was no evidence of a division of the EW into rostral and posterior subnuclei, nor for separate cell populations in the EW and the anterior median nucleus (AM). Expand
[Isolated nuclear oculomotor nerve palsy due to mesencephalic infarction].
It is clarified that such a small infarct disclosed only by MRI can cause isolated oculomotor nerve palsy and it is emphasized that the intraaxial ischemic lesion should be ruled out by using the sophisticated diagnostic aid before making diagnosis of peripheral lesion. Expand
Medial rectus subgroups of the oculomotor nucleus and their abducens internuclear input in the monkey
A new picture of the internal OMN organization is provided, and the physiological findings that the abducens internuclear pathway activates only MR motoneurons are supported. Expand
A case of bilateral oculomotor nuclear palsy.
A 61-year-old woman with two episodes of vertebrobasilar infarction with sudden onset of bilateral ptosis was concluded that she had an isolated, pupil-sparing, bilateral oculomotor nuclear palsy caused by midbrain infarct. Expand
Perioculomotor cell groups in monkey and man defined by their histochemical and functional properties: Reappraisal of the Edinger‐Westphal nucleus
The present results form the basis for addressing the appropriate functional cell groups in correlative clinicopathological studies, and for the first time, the MIF motoneurons could be identified around the medial aspect of the human oculomotor nucleus as a group of ChAT‐positive neurons that lack CSPG‐positive perineuronal nets. Expand