Intramembrane charge movement and sarcoplasmic calcium release in enzymatically isolated mammalian skeletal muscle fibres.

@article{Szentesi1997IntramembraneCM,
  title={Intramembrane charge movement and sarcoplasmic calcium release in enzymatically isolated mammalian skeletal muscle fibres.},
  author={P{\'e}ter Szentesi and Vincent Jacquemond and L{\'a}szl{\'o} Kov{\'a}cs and L{\'a}szl{\'o} Csernoch},
  journal={The Journal of physiology},
  year={1997},
  volume={505 ( Pt 2)},
  pages={371-84}
}
1. Single muscle fibres were dissociated enzymatically from the extensor digitorum longus and communis muscles of rats and guinea-pigs. The fibres were mounted into a double Vaseline gap experimental chamber and the events in excitation-contraction coupling were studied under voltage clamp conditions. 2. The voltage dependence of intramembrane charge movement followed a two-state Boltzmann distribution with maximal available charge of 26.1 +/- 1.5 and 26.1 +/- 1.3 nC microF-1, mid-point voltage… CONTINUE READING
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