Intralesional bleomycin sulfate therapy for warts. A novel bifurcated needle puncture technique.

@article{Shelley1991IntralesionalBS,
  title={Intralesional bleomycin sulfate therapy for warts. A novel bifurcated needle puncture technique.},
  author={W. Shelley and E. Shelley},
  journal={Archives of dermatology},
  year={1991},
  volume={127 2},
  pages={
          234-6
        }
}
A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment. 
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