Intralesional Bleomycin Injections for Vascular Malformations: A Systematic Review and Meta-Analysis.

@article{Horbach2016IntralesionalBI,
  title={Intralesional Bleomycin Injections for Vascular Malformations: A Systematic Review and Meta-Analysis.},
  author={S E R Horbach and Irma M. Rigter and J Henk Sillevis Smitt and Jim A. Reekers and P I Spuls and Chantal M A M van der Horst},
  journal={Plastic and reconstructive surgery},
  year={2016},
  volume={137 1},
  pages={244-56}
}
BACKGROUND Vascular malformations are congenital anomalies of the vascular system. Intralesional bleomycin injections are commonly used to treat vascular malformations. However, pulmonary fibrosis could potentially be a severe complication, known from systemic bleomycin therapy for malignancies. In this study, the authors investigate the effectiveness and safety of bleomycin (A2, B2, and A5) injections for vascular malformations, when possible relative to other sclerosants. METHODS The… CONTINUE READING