Intrahippocampal injections of somatostatin dissociate acquisition from the flexible use of place responses.

@article{Lamirault2001IntrahippocampalIO,
  title={Intrahippocampal injections of somatostatin dissociate acquisition from the flexible use of place responses.},
  author={La{\"e}titia Lamirault and J. C. Le Guillou and Jacques Micheau and Robert Jaffard},
  journal={The European journal of neuroscience},
  year={2001},
  volume={14 3},
  pages={567-70}
}
Previous studies showed that injections of somatostatin (SS-14) into the hippocampus facilitate the acquisition of spatial tasks in mice. The present study was aimed at better understanding the learning and memory processes that could be affected by hippocampal SS-14 stimulation. Balb/c mice were submitted to a two-stage learning paradigm. In stage 1, they were trained for acquisition of a spatial discrimination task in a radial maze and, in stage 2, were submitted to a probe test aiming at… CONTINUE READING