Intrahepatic bile duct destruction in a patient with sarcoidosis and chronic intrahepatic cholestasis.

@article{Nakanuma1979IntrahepaticBD,
  title={Intrahepatic bile duct destruction in a patient with sarcoidosis and chronic intrahepatic cholestasis.},
  author={Yasuni Nakanuma and Goroku Ohta and Yoji Yamazaki and Kenji Doishita},
  journal={Acta pathologica japonica},
  year={1979},
  volume={29 2},
  pages={211-9}
}
An autopsy case of sarcoidosis with chronic intrahepatic cholestasis for 2 and a half years was presented. Generalized distribution of noncaseating epithelioid granulomas and positive Kveim test were consistent with sarcoidosis. Histological examination of the liver revealed extensive bile duct destruction similar to that seen in the liver of primary biliary cirrhosis. Destructive cholangitis found in the liver appeared to be responsible for long term intrahepatic cholestasis, and no sarcoid… CONTINUE READING