Intrahepatic Lymphatic Invasion Independently Predicts Poor Survival and Recurrences after Hepatectomy in Patients with Colorectal Carcinoma Liver Metastases

@article{Korita2007IntrahepaticLI,
  title={Intrahepatic Lymphatic Invasion Independently Predicts Poor Survival and Recurrences after Hepatectomy in Patients with Colorectal Carcinoma Liver Metastases},
  author={Pavel Vladimirovich Korita and PhD Toshifumi Wakai and PhD Yoshio Shirai and PhD Jun Sakata and Kazuyasu Takizawa and PhD Pauldion V. Cruz and PhD Yoichi Ajioka and PhD FACS Katsuyoshi Hatakeyama},
  journal={Annals of Surgical Oncology},
  year={2007},
  volume={14},
  pages={3472-3480}
}
D2-40 monoclonal antibody immunoreactivity is specific for lymphatic endothelium and therefore provides a marker of lymphatic invasion. We hypothesized that intrahepatic lymphatic invasion reflects the nodal status of colorectal carcinoma liver metastases and may function as an adverse prognostic factor. A retrospective analysis of 105 consecutive patients who underwent resection for colorectal carcinoma liver metastases was conducted. Intrahepatic lymphatic invasion was declared when either… CONTINUE READING
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