Intragastric floating drug delivery system of cefuroxime axetil: in vitro evaluation.

@article{Patel2006IntragastricFD,
  title={Intragastric floating drug delivery system of cefuroxime axetil: in vitro evaluation.},
  author={Viral F. Patel and Natavarlal M. Patel},
  journal={AAPS PharmSciTech},
  year={2006},
  volume={7 1},
  pages={E17}
}
This investigation describes the development of an intragastric drug-delivery system for cefuroxime axetil. The 3(2) full factorial design was employed to evaluate contribution of hydroxypropyl methyl cellulose (HPMC) K4M/HPMC K100 LV ratio (polymer blend) and sodium lauryl sulfate (SLS) on drug release from HPMC matrices. Tablets were prepared using direct compression technique. Formulations were evaluated for in vitro buoyancy and drug release study using United States Pharmacopeia (USP) 24… CONTINUE READING
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