Intraflagellar transport molecules in ciliary and nonciliary cells of the retina

  title={Intraflagellar transport molecules in ciliary and nonciliary cells of the retina},
  author={Tina Sedmak and Uwe Wolfrum},
  booktitle={The Journal of cell biology},
The assembly and maintenance of cilia require intraflagellar transport (IFT), a process mediated by molecular motors and IFT particles. Although IFT is a focus of current intense research, the spatial distribution of individual IFT proteins remains elusive. In this study, we analyzed the subcellular localization of IFT proteins in retinal cells by high resolution immunofluorescence and immunoelectron microscopy. We report that IFT proteins are differentially localized in subcompartments of… CONTINUE READING


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Photoreceptors and intraflagellar transport

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  • Photoreceptor cell biology and inherited retinal…
  • 2004
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