Intraepithelial neoplasia in the anal canal. The appearance and relation to genital neoplasia.

@article{Fenger1986IntraepithelialNI,
  title={Intraepithelial neoplasia in the anal canal. The appearance and relation to genital neoplasia.},
  author={Claus Fenger and V T Nielsen},
  journal={Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology},
  year={1986},
  volume={94 5},
  pages={343-9}
}
Anal canal intraepithelial neoplasia (ACIN) in the form of squamous dysplasia and carcinoma in situ is a rare condition. In this paper we present all 19 cases diagnosed in Denmark in a two-year period. The incidence was 0.2/10(5)/year compared to 0.7/10(5)/year for variants of squamous carcinoma in the anal canal. Most cases of ACIN were incidental findings at minor anal surgery. Histologically, one half of the lesions were located in the anal transitional zone above the dentate line. Two of… CONTINUE READING