Intraductal injection of LPS as a mouse model of mastitis: signaling visualized via an NF-κB reporter transgenic.

Abstract

Animal models of human disease are necessary in order to rigorously study stages of disease progression and associated mechanisms, and ultimately, as pre-clinical models to test interventions. In these methods, we describe a technique in which lipopolysaccharide (LPS) is injected into the lactating mouse mammary gland via the nipple, effectively modeling… (More)
DOI: 10.3791/4030

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