Intractable seizure disorder associated with chronic herpes infection HSV1 detection in tissue by the polymerase chain reaction


We describe the pathological findings and report the detection of herpes simplex virus 1 (HSV1) in the brain in three patients who presented with intractable seizures. All three patients had a previous history of HSV1 encephalitis and went on to develop a medically refractory seizure disorder necessitating surgical intervention. HSV1 encephalitis was… (More)
DOI: 10.1007/s003810050167


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