Intractable seizure disorder associated with chronic herpes infection HSV1 detection in tissue by the polymerase chain reaction

Abstract

We describe the pathological findings and report the detection of herpes simplex virus 1 (HSV1) in the brain in three patients who presented with intractable seizures. All three patients had a previous history of HSV1 encephalitis and went on to develop a medically refractory seizure disorder necessitating surgical intervention. HSV1 encephalitis was… (More)
DOI: 10.1007/s003810050167

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