Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits.

@article{Uvebrant1994IntractableEI,
  title={Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits.},
  author={Paul Uvebrant and R Bauzien{\`e}},
  journal={Neuropediatrics},
  year={1994},
  volume={25 6},
  pages={284-9}
}
Fifty children and adolescents with intractable epilepsy were treated with lamotrigine. Most of the children had other neuro-impairments, such as mental retardation, cerebral palsy and autism, added to their epilepsy. Five stopped lamotrigine treatment within four months because of side effects. In the 45 children who continued treatment for a mean of 14 months, five became seizure-free and in 16 the seizure frequency was reduced more than 30 percent. Absences and complex partial seizures… CONTINUE READING