Intracranial self-stimulation induces Fos expression in GABAergic neurons in the rat mesopontine tegmentum.

@article{Nakahara2001IntracranialSI,
  title={Intracranial self-stimulation induces Fos expression in GABAergic neurons in the rat mesopontine tegmentum.},
  author={Daiichiro Nakahara and Yasushi Ishida and Michiko Nakamura and Nobuaki Furuno and Toshikazu Nishimori},
  journal={Neuroscience},
  year={2001},
  volume={106 3},
  pages={633-41}
}
The cholinergic neurons which originate in the mesopontine tegmentum and innervate the midbrain ventral tegmental area have been proposed to play a key role in intracranial self-stimulation reward. This mesopontine area also contains GABA neurons. Detailed information is still lacking, however, about the relationship of cholinergic and GABAergic neurons in this region to self-stimulation reward. Therefore, using double immunostaining for Fos as a marker of neuronal activity and choline… CONTINUE READING