Intracranial hemorrhage and vitamin K deficiency associated with biliary atresia: summary of 15 cases and review of the literature.

@article{Akiyama2006IntracranialHA,
  title={Intracranial hemorrhage and vitamin K deficiency associated with biliary atresia: summary of 15 cases and review of the literature.},
  author={Hideyuki Akiyama and Yusuke Okamura and Tatsuya Nagashima and Akiko Yokoi and Toshihiro Muraji and Yoshiyuki Uetani},
  journal={Pediatric neurosurgery},
  year={2006},
  volume={42 6},
  pages={362-7}
}
Biliary atresia (BA) is a rare disease, characterized by progressive and obliterative cholangiopathy, and is one of the major causes of secondary vitamin K deficiency in infancy. We describe 15 infants (10 female, 5 male) with BA, presenting with intracranial hemorrhage (ICH), including 10 subdural hemorrhages, 4 subarachnoid hemorrhages, 2 intraventricular hemorrhages, and 1 intraparenchymal hemorrhage. The age at onset of ICH ranged from 26 to 79 (mean 54.2) days. Eight patients underwent… CONTINUE READING