Intracranial ependymomas of childhood: current management strategies.

  title={Intracranial ependymomas of childhood: current management strategies.},
  author={Matthew D. Smyth and Biljana N. Horn and Carla Russo and Mitchel S. Berger},
  journal={Pediatric neurosurgery},
  volume={33 3},
Children with intracranial ependymomas have relatively poor outcomes despite the low-grade histology of these tumors and recent advances in diagnosis, microneurosurgical resection, and adjuvant therapy. Aggressive surgical resection and postoperative adjuvant therapy result in only a 5-year survival rate of 50%. In this paper, we provide a review of the current technical aspects of surgical resection, and focus on recent studies of the epidemiology, molecular markers, prognostic factors and… CONTINUE READING


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