Intracranial Nonthermal Irreversible Electroporation: In Vivo Analysis

  title={Intracranial Nonthermal Irreversible Electroporation: In Vivo Analysis},
  author={Paulo A. Garcia and J. Rossmeisl and R. Neal and T. Ellis and J. D. Olson and N. Henao-Guerrero and J. Robertson and R. Davalos},
  journal={The Journal of Membrane Biology},
  • Paulo A. Garcia, J. Rossmeisl, +5 authors R. Davalos
  • Published 2010
  • Medicine, Chemistry
  • The Journal of Membrane Biology
  • Nonthermal irreversible electroporation (NTIRE) is a new minimally invasive technique to treat cancer. It is unique because of its nonthermal mechanism of tumor ablation. Intracranial NTIRE procedures involve placing electrodes into the targeted area of the brain and delivering a series of short but intense electric pulses. The electric pulses induce irreversible structural changes in cell membranes, leading to cell death. We correlated NTIRE lesion volumes in normal brain tissue with electric… CONTINUE READING
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