Intracoronary pressure and flow velocity with sensor-tip guidewires: a new methodologic approach for assessment of coronary hemodynamics before and after coronary interventions.

@article{Serruys1993IntracoronaryPA,
  title={Intracoronary pressure and flow velocity with sensor-tip guidewires: a new methodologic approach for assessment of coronary hemodynamics before and after coronary interventions.},
  author={Patrick Wjc Serruys and Carlo Di Mario and Nicolas Meneveau and Peter de Jaegere and Sipke Strikwerda and Pim J. de Feyter and H{\aa}kan Emanuelsson},
  journal={The American journal of cardiology},
  year={1993},
  volume={71 14},
  pages={
          41D-53D
        }
}
The use of miniaturized pressure and velocity sensors mounted on angioplasty guidewires allows the simultaneous measurement of coronary blood flow velocity and transstenotic pressure gradient, 2 parameters that, combined, should perfectly characterize stenosis hemodynamics. The aim of this article is assessment of the changes in coronary blood flow velocity observed with a Doppler-tipped angioplasty guidewire in 35 patients undergoing balloon angioplasty. We also report our initial experience… Expand
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References

SHOWING 1-10 OF 56 REFERENCES
Intracoronary blood flow velocity and transstenotic pressure gradient using sensor-tip pressure and Doppler guidewires: a new technology for the assessment of stenosis severity in the catheterization laboratory.
TLDR
The combined use of a pressure and a Doppler guidewire provides a complete assessment of the transstenotic pressure/coronary flow velocity relation at rest and after pharmacologically induced hyperemia and allows the characterization of stenosis hemodynamics and functional severity. Expand
Coronary blood flow velocity during percutaneous transluminal coronary angioplasty as a guide for assessment of the functional result.
TLDR
The application of the Doppler technique may provide a new method of on-line functional monitoring of the PTCA procedure in individual patients, but does not yet allow an accurate prediction of the change in coronary geometry brought about by P TCA. Expand
How to assess the immediate results of PTCA. Should we use pressure gradient, flow reserve or minimal luminal cross-sectional area?
TLDR
Coronary flow reserve was measured pre- and post-angioplasty by digital subtraction cineangiography, and intracoronary blood flow velocity measurements with a Doppler probe, and the radiographic assessment of myocardial perfusion with contrast media were applied to measure the immediate improvement in coronary flow reserve. Expand
Values and limitations of transstenotic pressure gradients measured during percutaneous coronary angioplasty.
TLDR
Flow in the great cardiac vein was measured in 13 patients before and/or after angioplasty of a proximal left anterior descending stenosis, not filled by collaterals, to assess the values and limitations of the in vivo measurements of the pressure gradient versus the calculated values. Expand
Validation of a Doppler Guide Wire for Intravascular Measurement of Coronary Artery Flow Velocity
TLDR
The Doppler guide wire measures phasic flow velocity patterns and linearly tracks changes in flow rate in small, straight coronary arteries and should facilitate measurement ofphasic coronary flow velocity during coronary angiography and angioplasty. Expand
Initial experiences with a miniaturized pressure transducer during coronary angioplasty.
TLDR
A newly constructed pressure sensor with a diameter of 0.45 mm was evaluated in 15 patients undergoing balloon coronary angioplasty (PTCA) and delivers recordings of good quality and may be especially of interest during angiopLasty due to its small diameter. Expand
Alterations of phasic coronary artery flow velocity in humans during percutaneous coronary angioplasty.
TLDR
Flow velocity measurements may be performed distal to a coronary stenosis with the Doppler guide wire and changes in distal flow velocity patterns and diastolic/systolic velocity ratio appeared to be more relevant than the hyperemic response in assessing the immediate physiologic outcome of coronary angioplasty. Expand
Limitations of the zero crossing detector in the analysis of intracoronary Doppler: a comparison with fast Fourier transform analysis of basal, hyperemic, and transstenotic blood flow velocity measurements in patients with coronary artery disease.
TLDR
The aim of this study is the comparison of a conventional ZC detector and a custom-designed spectral analyzer in the analysis of intracoronary Doppler signals obtained in 19 patients undergoing coronary angioplasty. Expand
Determinants of transstenotic gradients observed during angioplasty: an experimental model.
TLDR
The transstenotic gradient measured at angioplasty overestimates "true" resting gradient in a predictable manner, which is dependent on the ratio of Dc to Ds. Expand
The effect of coronary angioplasty on coronary flow reserve.
TLDR
It is demonstrated that in one-half of patients there is a transient reduction in coronary flow reserve immediately after angioplasty, which may not reflect the eventual success of the procedure in removing physiologic obstruction to coronary blood flow. Expand
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