Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety.

@article{Bartunek2005IntracoronaryIO,
  title={Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety.},
  author={Jozef J. Bartunek and Marc Vanderheyden and Bart Vandekerckhove and Samer Mansour and Bernard de Bruyne and Pieter de Bondt and Inge Van Haute and Nele Lootens and Guy R. Heyndrickx and William Wijns},
  journal={Circulation},
  year={2005},
  volume={112 9 Suppl},
  pages={I178-83}
}
BACKGROUND Bone marrow CD133-positive (CD133+) cells possess high hematopoietic and angiogenic capacity. We tested the feasibility, safety, and functional effects of the use of enriched CD133+ progenitor cells after intracoronary administration in patients with recent myocardial infarction. METHODS AND RESULTS Among 35 patients with acute myocardial infarction treated with stenting, 19 underwent intracoronary administration of CD133+ progenitor cells (12.6+/-2.2 x 10(6) cells) 11.6+/-1.4 days… CONTINUE READING
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