Intracoronary Injection of CD133-Positive Enriched Bone Marrow Progenitor Cells Promotes Cardiac Recovery After Recent Myocardial Infarction: Feasibility and Safety

@article{Bartunek2005IntracoronaryIO,
  title={Intracoronary Injection of CD133-Positive Enriched Bone Marrow Progenitor Cells Promotes Cardiac Recovery After Recent Myocardial Infarction: Feasibility and Safety},
  author={J. Bartunek and M. Vanderheyden and B. Vandekerckhove and S. Mansour and B. De Bruyne and P. de Bondt and I. Van haute and Nele Lootens and G. Heyndrickx and W. Wijns},
  journal={Circulation},
  year={2005},
  volume={112},
  pages={I178-I183}
}
Background—Bone marrow CD133-postive (CD133+) cells possess high hematopoietic and angiogenic capacity. We tested the feasibility, safety, and functional effects of the use of enriched CD133+ progenitor cells after intracoronary administration in patients with recent myocardial infarction. Methods and Results—Among 35 patients with acute myocardial infarction treated with stenting, 19 underwent intracoronary administration of CD133+ progenitor cells (12.6±2.2×106 cells) 11.6±1.4 days later… Expand

Paper Mentions

Interventional Clinical Trial
The aim of this study is to evaluate if the intracoronary infusion of autologous bone-marrow derived CD133+ endothelial precursor cells is able to promote neovascularization and to… Expand
ConditionsCoronary Artery Disease
InterventionProcedure
Pilot study to evaluate the safety and feasibility of intracoronary CD133+ and CD133− CD34+ cell therapy in patients with nonviable anterior myocardial infarction
  • A. Manginas, E. Goussetis, +8 authors D. Cokkinos
  • Medicine
  • Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • 2007
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Experimental and Clinical Regenerative Capability of Human Bone Marrow Cells After Myocardial Infarction
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