Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14

@inproceedings{Fischer2016IntraclonalGD,
  title={Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14},
  author={Sebastian Fischer and Jens Klockgether and Patricia Moran Losada and Philippe Chouvarine and Nina Cramer and Colin F. Davenport and Sarah Dethlefsen and Marie Dorda and Alexander Goesmann and Rolf Hilker and Samira Mielke and Torben Sch{\"o}nfelder and Sebastian Suerbaum and Oliver Tuerk and Sabrina Woltemate and Lutz Wiehlmann and Burkhard T{\"u}mmler},
  booktitle={Environmental microbiology reports},
  year={2016}
}
Bacterial populations differentiate at the subspecies level into clonal complexes. Intraclonal genome diversity was studied in 100 isolates of the two dominant Pseudomonas aeruginosa clones C and PA14 collected from the inanimate environment, acute and chronic infections. The core genome was highly conserved among clone members with a median pairwise within-clone single nucleotide sequence diversity of 8 × 10(-6) for clone C and 2 × 10(-5) for clone PA14. The composition of the accessory genome… CONTINUE READING
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