Intracisternally given Elastase/e/enhances Blood-brain Barrier/bbb/ Permeability in Newborn Piglets

Abstract

Elastase, released during polymorphonuclear phagocytosis, is a potentially tissue damaging enzyme. We investigated its effect on BBB-permeability in newborn piglets. 11 anesthetized animals /Group 1/ were given 1 μg porcine E in 0,5 ml artificial CSF intracisternally, 7 piglets (given mock CSE) served as controls /Group 2. Through 4 hours afler E… (More)
DOI: 10.1203/00006450-199211000-00105

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