Intracisternal injection of a TRH analogue stimulates gastric luminal serotonin release in rats.

@article{Stephens1989IntracisternalIO,
  title={Intracisternal injection of a TRH analogue stimulates gastric luminal serotonin release in rats.},
  author={Robert Louis Stephens and Yvette F. Tach{\'e}},
  journal={The American journal of physiology},
  year={1989},
  volume={256 2 Pt 1},
  pages={G377-83}
}
Intracisternal injection of TRH analogue, RX 77368, which has been previously shown to induce a vagal-dependent stimulation of gastric acid secretion and contractility dose-dependently (10-300 ng) stimulated serotonin release into the gastric lumen of conscious pylorus-ligated rats. The stimulation of gastric acid and serotonin release occurred 15 and 30 min, respectively, after intracisternal injection of RX 77368 (100 ng) and lasted for over 2 h, as measured in urethan-anesthetized rats with… CONTINUE READING