Intracerebroventricular injections of cholecystokinin octapeptide suppress feeding in rats--pharmacological characterization of this action.

@article{Schick1986IntracerebroventricularIO,
  title={Intracerebroventricular injections of cholecystokinin octapeptide suppress feeding in rats--pharmacological characterization of this action.},
  author={Rafael Reinhold Schick and Tony L. Yaksh and Vay Liang W. Go},
  journal={Regulatory peptides},
  year={1986},
  volume={14 4},
  pages={277-91}
}
Cholecystokinin octapeptide (CCK-8), administered intracerebroventricularly (i.c.v.), will suppress feeding. The aim of the present study was to determine the pharmacological characteristics of this satiety inducing effect in rats. For this purpose, we employed a feeding bioassay model in 24 h fasted rats and examined the effects of CCK-8 and a variety of… CONTINUE READING