Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke.

@article{Borlongan2004IntracerebralTO,
  title={Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke.},
  author={Cesario V. Borlongan and Steve J M Skinner and Marilyn S. Geaney and Alfred V Vasconcellos and Robert B. Elliott and Dwaine F. Emerich},
  journal={Stroke},
  year={2004},
  volume={35 9},
  pages={2206-10}
}
BACKGROUND AND PURPOSE Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS In vitro studies involved serum deprivation of rat embryonic cortical neurons and treatment with a range of concentrations of conditioned media from CP. For in vivo studies, rats received a 1-hour middle cerebral artery occlusion followed by intracranial… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 45 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Similar Papers

Loading similar papers…