Intracerebral Hemorrhage Induces Cardiac Dysfunction in Mice Without Primary Cardiac Disease

@inproceedings{Li2018IntracerebralHI,
  title={Intracerebral Hemorrhage Induces Cardiac Dysfunction in Mice Without Primary Cardiac Disease},
  author={Wei Li and Linlin Li and Michael Chopp and Poornima Venkat and Alex Zacharek and Zhili Chen and Julie Landschoot-Ward and Tao Yan and Jieli Chen},
  booktitle={Front. Neurol.},
  year={2018}
}
Background: Intracerebral hemorrhage (ICH) is a life threatening stroke subtype and a worldwide health problem. In this study, we investigate brain-heart interaction after ICH in mice and test whether ICH induces cardiac dysfunction in the absence of primary cardiac disease. We also investigate underlying mechanisms such as oxidative stress and inflammatory responses in mediating cardiac dysfunction post-ICH in mice. Methods: Male, adult (3-4 m) C57BL/6J mice were subjected to sham surgery or… CONTINUE READING
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