IntracellularStaphylococcus aureus: A MECHANISM FOR THE INDOLENCE OF OSTEOMYELITIS

@article{Ellington2003IntracellularStaphylococcusAA,
  title={IntracellularStaphylococcus aureus: A MECHANISM FOR THE INDOLENCE OF OSTEOMYELITIS},
  author={John Kent Ellington and Mitchel Byron Harris and Lawrence X. Webb and Beth P. Smith and Timothy L Smith and Kok-keong Tan and Mark Falco Sanders Hudson},
  journal={The Journal of bone and joint surgery. British volume},
  year={2003},
  volume={85 6},
  pages={
          918-21
        }
}
Staphylococcus aureus is the bacterial pathogen which is responsible for approximately 80% of all cases of human osteomyelitis. It can invade and remain within osteoblasts. The fate of intracellular Staph. aureus after the death of the osteoblast has not been documented. We exposed human osteoblasts to Staph. aureus. After infection, the osteoblasts were either lysed with Triton X-100 or trypsinised. The bacteria released from both the trypsinised and lysed osteoblasts were cultured and counted… CONTINUE READING
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