Intracellular zinc homeostasis and zinc signaling.

  title={Intracellular zinc homeostasis and zinc signaling.},
  author={Masaaki Murakami and Toshio Hirano},
  journal={Cancer science},
  volume={99 8},
Zinc (Zn) is an essential heavy metal that is incorporated into a number of human Zn metalloproteins. Zn plays important roles in nucleic acid metabolism, cell replication, and tissue repair and growth. Zn deficiency is associated with a range of pathological conditions, including impaired immunity, retarded growth, brain development disorders and delayed wound healing. Moreover, many reports have suggested that Zn is involved in cancer development and levels of Zn in serum and malignant… CONTINUE READING
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