Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions.

@article{Cronholm2013IntracellularUA,
  title={Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions.},
  author={Pontus Cronholm and Hanna L Karlsson and Jonas Hedberg and Troy A. Lowe and Lina Winnberg and Karine Elihn and Inger Odnevall Wallinder and Lennart M{\"o}ller},
  journal={Small},
  year={2013},
  volume={9 7},
  pages={
          970-82
        }
}
UNLABELLED An increased understanding of nanoparticle toxicity and its impact on human health is essential to enable a safe use of nanoparticles in our society. The aim of this study is to investigate the role of a Trojan horse type mechanism for the toxicity of Ag-nano and CuO-nano particles and their corresponding metal ionic species (using CuCl2 and AgNO3 ), i.e., the importance of the solid particle to mediate cellular uptake and subsequent release of toxic species inside the cell. The… CONTINUE READING
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