Intracellular trafficking of solid lipid nanoparticles and their distribution between cells through tunneling nanotubes.

@article{Kristl2013IntracellularTO,
  title={Intracellular trafficking of solid lipid nanoparticles and their distribution between cells through tunneling nanotubes.},
  author={Julijana Kristl and Karmen Teska{\vc} Plajn{\vs}ek and Mateja Erdani Kreft and Biljana Jankovi{\'c} and Petra Kocbek},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2013},
  volume={50 1},
  pages={
          139-48
        }
}
The intracellular fate of nanosized drug delivery systems is still not well understood. Various internalization pathways have been discovered, but knowledge of their intracellular trafficking is still incomplete. The aim of this study was to examine the internalization, pathways, and positioning taken by solid lipid nanoparticles (SLNs) in cells. SLNs were fluorescence labeled with a newly synthesized fluorescent probe, 14-DACA. The probe was strongly incorporated into the nanoparticle core… CONTINUE READING
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