Intracellular survival of Burkholderia cepacia complex isolates in the presence of macrophage cell activation.

@article{Saini1999IntracellularSO,
  title={Intracellular survival of Burkholderia cepacia complex isolates in the presence of macrophage cell activation.},
  author={L S Saini and Stephen Galsworthy and Maie A R St John and Miguel A Valvano},
  journal={Microbiology},
  year={1999},
  volume={145 ( Pt 12)},
  pages={3465-75}
}
Strains of the Burkholderia cepacia complex have emerged as a serious threat to patients with cystic fibrosis due to their ability to infect the lung and cause, in some patients, a necrotizing pneumonia that is often lethal. It has recently been shown that several strains of the B. cepacia complex can escape intracellular killing by free-living amoebae following phagocytosis. In this work, the ability of two B. cepacia complex strains to resist killing by macrophages was explored. Using… CONTINUE READING

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