Intracellular study of rat entopeduncular nucleus neurons in an in vitro slice preparation: electrical membrane properties

@article{Nakahishi1990IntracellularSO,
  title={Intracellular study of rat entopeduncular nucleus neurons in an in vitro slice preparation: electrical membrane properties},
  author={Hidekazu Nakahishi and Hitoshi Kita and Stephen T. Kitai},
  journal={Brain Research},
  year={1990},
  volume={527},
  pages={81-88}
}
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63 Citations
Highly Influential Citations
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Background Citations
27
Methods Citations
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Results Citations
11

63 Citations

Intracellular study of rat entopeduncular nucleus neurons in an in vitro slice preparation: response to subthalamic stimulation

Intracellular study of rat globus pallidus neurons: membrane properties and responses to neostriatal, subthalamic and nigral stimulation

Effects of dynorphin on rat entopeduncular nucleus neurons in vitro

Electrophysiological properties of cholinergic and noncholinergic neurons in the ventral pallidal region of the nucleus basalis in rat brain slices.

TLDR
Cholinergic pallidal neurons in brain slices from 6- to 18-day-old rats have similar properties to magnocellular cholinergic neurons in other parts of the forebrain, except that they exhibit strong spike accommodation.

High frequency stimulation or elevated K+ depresses neuronal activity in the rat entopeduncular nucleus

Electrophysiological characterization of entopeduncular nucleus neurons in anesthetized and freely moving rats

TLDR
The data support the existence of two distinct neuronal populations in the rat EP that can be distinguished by their characteristic firing response to anesthesia, and help reconcile in vitro studies in rats and primates which have reported two distinct populations.

Enhanced Ih depresses rat entopeduncular nucleus neuronal activity from high-frequency stimulation or raised Ke+.

TLDR
It is shown that the hyperpolarization-activated (I(h) channel mediates the HFS- or K(+)-induced depression of EP neuronal activity and could underlie the inhibitory effects of HFS used in deep brain stimulation in output basal ganglia nuclei.

Cholinergic mechanisms of high-frequency stimulation in entopeduncular nucleus.

TLDR
This study for the first time describes a cholinergic mechanism of HFS in EP neurons and provides new insight into the underlying mechanisms of DBS, suggesting that muscarinic receptor activation during HFS can lead to feedforward excitation through the opening of CAN channels.

Subthalamic nucleus evokes similar long lasting glutamatergic excitations in pallidal, entopeduncular and nigral neurons in the basal ganglia slice

Neostriatal and globus pallidus stimulation induced inhibitory postsynaptic potentials in entopeduncular neurons in rat brain slice preparations

...

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Electrical membrane properties of rat subthalamic neurons in an in vitro slice preparation

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The responses of cerebellar nuclear cells to extracellular stimulation in a slice preparation were studied and the ionic basis of their electroresponsiveness was investigated with blockers of…

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TLDR
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