Intracellular signaling pathways in IgE-dependent mast cell activation

@article{Kope2006IntracellularSP,
  title={Intracellular signaling pathways in IgE-dependent mast cell activation},
  author={Agnieszka Kope{\'c} and Bernard Panaszek and Andrzej Mariusz Fal},
  journal={Archivum Immunologiae et Therapiae Experimentalis},
  year={2006},
  volume={54},
  pages={393-401}
}
Abstract.Mast cells (MCs) are both central effectors and signaling cells in allergic reactions. Their key role in the immunopathology of asthma and other allergic diseases has been well documented. Molecular events leading to MC activation have not been yet fully established, however. Recent studies emphasize the key role of the protein tyrosine kinases Lyn and Fyn in MC signal transduction. The finding that Lyn kinase negatively regulates MC degranulation and that Fyn kinase enhances this… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 101 REFERENCES

Negative Regulation of Immunoglobulin E–dependent Allergic Responses by Lyn Kinase

  • The Journal of experimental medicine
  • 2004
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL