Intracellular signaling molecules involved in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells.

@article{Guan2007IntracellularSM,
  title={Intracellular signaling molecules involved in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells.},
  author={Cha-Xiang Guan and Penggang Liu and Min Zhang and Hong Bo Bai and Ravitej Khunkhun and Xiang Fang},
  journal={Peptides},
  year={2007},
  volume={28 9},
  pages={
          1667-73
        }
}
Vasoactive intestinal peptide (VIP), a non-adrenergic, non-cholinergic neuromediator, plays an important role in maintaining the bronchial tone of the airway and has anti-inflammatory properties. Recently, we reported that VIP enhances wound repair in human bronchial epithelial cells (HBEC). In the present study, we have identified the intracellular signaling molecules that are involved in VIP-mediated wound healing in HBEC. The effects of VIP on wound repair of HBEC were partially blocked by H… CONTINUE READING

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