Intracellular signal modulation: a pivotal role for protein kinase C.

  title={Intracellular signal modulation: a pivotal role for protein kinase C.},
  author={Gullermina Casabona},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  volume={21 3},
1. Protein Kinase C represents a family of Ca(2+)- and phospholipid-dependent enzymes which catalyzes the covalent transfer of phosphate from ATP to serine and threonine residues on proteins. Phosphorylation of the substrate protein induces a conformational change and thereby a modification of its functional properties. 2. PKC family consists of at least twelve members, divided in three subgroups:classical PKCs, (alpha, beta I, beta II, gamma), new PKCs, (delta, epsilon, eta, theta, mu) and… CONTINUE READING


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