Intracellular processes associated with vesicular transport from endoplasmic reticulum to Golgi and exocytosis: ethanol-induced changes in membrane biogenesis.

@article{Slomiany1994IntracellularPA,
  title={Intracellular processes associated with vesicular transport from endoplasmic reticulum to Golgi and exocytosis: ethanol-induced changes in membrane biogenesis.},
  author={Amalia Slomiany and Maria Grabska and E Piotrowski and S Sengupta and M Morita and Chinnaswamy Kasinathan and B. L. Slomiany},
  journal={Archives of biochemistry and biophysics},
  year={1994},
  volume={310 1},
  pages={
          247-55
        }
}
Membrane biogenesis, expressed in endoplasmic reticulum (ER) by formation of transport vesicles, was studied in the liver of ethanol-fed and pair-fed rats. In ER of ethanol-fed animals, the endogenous synthesis of phosphatidylcholine (PC) and its contribution to ER transport vesicles were reduced by 50%, as compared to that in pair-fed controls. Reduction of PC synthesis and of its presence in ER-transport vesicles was also observed in pair-fed controls when the native cytosol was replaced with… 
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