Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens.

Abstract

OBJECTIVE To evaluate the potential for a pharmacologic mechanism to explain suboptimal virologic responses observed in a triple-nucleoside only regimen containing tenofovir disoproxil fumarate (TDF), abacavir (ABC), and lamivudine (3TC). METHODS This was a prospective evaluation of intracellular concentrations and pharmacokinetics of tenofovir… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.