Intracellular pH regulation in rabbit renal medullary collecting duct cells. Role of chloride-bicarbonate exchange.

@article{Zeidel1986IntracellularPR,
  title={Intracellular pH regulation in rabbit renal medullary collecting duct cells. Role of chloride-bicarbonate exchange.},
  author={Mark Lawrence Zeidel and Patricio da Silva and Julian Lawrence Seifter},
  journal={The Journal of clinical investigation},
  year={1986},
  volume={77 5},
  pages={1682-8}
}
The renal medullary collecting duct (MCD) secretes protons into its lumen and HCO3 into its basolateral space. Basolateral HCO3 transport is thought to occur via Cl/HCO3 exchange. To further characterize this Cl/HCO3 exchange process, intracellular pH (pHi) regulation was monitored in freshly prepared rabbit outer MCD cells. Cells were separated by protease… CONTINUE READING