Intracellular pH as a determinant of vascular smooth muscle function.

  title={Intracellular pH as a determinant of vascular smooth muscle function.},
  author={Ichiro Wakabayashi and Michael Poteser and Klaus Groschner},
  journal={Journal of vascular research},
  volume={43 3},
Intracellular pH (pHi) is a physiological parameter that is intimately linked to contractility, growth and proliferation of vascular smooth muscle (VSM). Regarding contractility, no general unifying concept of pHi regulation but a rather complex relation between pHi signals and vascular tone has been revealed so far. The modulation of vasotone by pHi depends on the type of blood vessel as well as on the pattern of regulatory input signals. In addition, changes in pHi have been recognized as an… CONTINUE READING

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